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papB [2018-02-13T05:44:02.000Z]

Xaa-Pro amino-peptidase

locus

BSU13860

5.17

40.18 kDa

protein length

363 aa Sequence Blast

gene length

1089 bp Sequence Blast

function

degradation of proline-containing peptides

product

Xaa-Pro amino-peptidase

essential

3.4.11.9

synonyms

ykvY

Outlinks

KEGG BsubCyc SubtiList UniProt Expression Browser

Genomic Context

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categories

[category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.3|Utilization of nitrogen sources other than amino acids] → [category|SW 2.3.3.4|Utilization of peptides]

[category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.6|Coping with hyper-osmotic stress]

Gene

Coordinates

1,453,691 → 1,454,782

The protein

Protein family

peptidase M24B family (according to Swiss-Prot)

Paralogous protein(s)

[protein|33886A1EAC13B684E92BF94201C46617AD2844B3|PapA]

Structure

[PDB|3Q6D] (''B. anthracis'' Xaa-Pro dipeptidase, 35% identity, 55% similarity)

Expression and Regulation

Operons

genes

[gene|C95EEAC79B9E823BBBCF6B1960DABCCBB2AC03A4|papB]

description

[Pubmed|22383849]

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genes

description

[Pubmed|22383849]

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Biological materials

Mutant

MGNA-B330 (ykvY::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1329 NBRP B. subtilis, Japan]

BKE13860 (Δ[gene|C95EEAC79B9E823BBBCF6B1960DABCCBB2AC03A4|papB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE13860 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACTTCTTGTTCCTCCCTGC, downstream forward: _UP4_TAATAGAAATAAAAAAGGAC

BKK13860 (Δ[gene|C95EEAC79B9E823BBBCF6B1960DABCCBB2AC03A4|papB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK13860 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACTTCTTGTTCCTCCCTGC, downstream forward: _UP4_TAATAGAAATAAAAAAGGAC

References

23144141